DMSO IN CELL CRYOPRESERVATION: A DOUBLE-EDGED SWORD WITH EVOLVING INNOVATIONS

As a cornerstone of cryobiology since its discovery in 1959, dimethyl sulfoxide (DMSO) has enabled breakthroughs in preserving cells and tissues for medical and research applications. But how does it work, and what challenges does it present? Let’s dive deeper.Why DMSO? Key Mechanisms Ice Inhibition:· Penetrates cell membranes, re

Feline hepatocytes are versatile tools in scientific research due to their unique biological characteristics. In basic cell biology research, they are used to study metabolic mechanisms, such as lipid, carbohydrate, and protein metabolism, as well as detoxification processes like glutathione metabolism. Their subcellular structures, including mitoc